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Documenting and Characterising the Various MRI Brain Changes

Who: Murdoch Children’s Research Institute

Where: Melbourne

About:

RCH have been documenting and characterising various MRI brain changes in children with NF1 since its inception in 2015.  

While there are some studies that have previously described common brain MRI findings in NF1, the results are incomplete and further changes have been seen anecdotally, but not yet described in the literature.

This study aims to quantify the incidence of abnormal MRI brain findings such as T2 hyperintensities, gliomas, Moyamoya syndrome, and aqueductal stenosis.


Funded projects

Tint: Mek Inhibitor trial
New Gene Editing Technology (CRISPR)
Neurofibromatosis Type 1 Severity Scale
Children with NF1 & Auditory Processing Deficits + Speech Perception Problems
Predicators of Autism in NF1: Development in Adolescence (PANDA)
Documenting and characterising the various MRI brain changes
Cell-free Bio bank